COVID-19

The temporal association of introducing and lifting non-pharmaceutical interventions with the time-varying reproduction number (R) of SARS-CoV-2: a modelling study across 131 countries – The Lancet Infectious Diseases

Methods  Data sources In this modelling study, we included data on country-level estimates of R from the EpiForecasts project by the London School of Hygiene & Tropical Medicine (London, UK). 12 Abbott S Hellewell J Thompson R et al. Estimating the time-varying reproduction number of SARS-CoV-2 using national and subnational case counts [version 1; peer review: awaiting peer review].   Briefly, the instantaneous reproduction number is estimated based on the daily counts of confirmed COVID-19 cases reported by the European Centre for Disease Prevention and Control. The instantaneous reproduction number represents the average number of secondary cases that would arise… Lire la suite »The temporal association of introducing and lifting non-pharmaceutical interventions with the time-varying reproduction number (R) of SARS-CoV-2: a modelling study across 131 countries – The Lancet Infectious Diseases

En Allemagne, contre le Covid, les écoles ouvrent les fenêtres | Reporterre

Hambourg (Allemagne), correspondance Dans la classe de Jan Basczok, le rituel est bien rôdé. Toutes les vingt minutes, les élèves ouvrent les fenêtres au fond de la salle. Le professeur d’histoire du lycée Nelson-Mandela de Hambourg, lui, ouvre la porte pour faire un courant d’air. En ce matin d’automne frais et humide, ses quinze lycéens ont gardé leurs gros pulls. Certains portent même leur écharpe. « Quand il fait suffisamment bon, on laisse les fenêtres ouvertes en permanence », raconte l’enseignant. Ce drôle de manège n’est pas une lubie de Jan Basczok mais une obligation pour les 33.000 établissements scolaires d’Allemagne depuis… Lire la suite »En Allemagne, contre le Covid, les écoles ouvrent les fenêtres | Reporterre

On the effect of age on the transmission of SARS-CoV-2 in households, schools and the community | The Journal of Infectious Diseases | Oxford Academic

Methods We reviewed published studies/data on detection of SARS-CoV-2 infection in contacts of COVID-19 cases, serological studies, and studies of infections in schools. Results Compared to younger/middle aged adults, susceptibility to infection for children aged under 10y is estimated to be significantly lower, while estimated susceptibility to infection in adults aged over 60y is higher. Serological studies suggest that younger adults (particularly those aged under 35y) often have high cumulative incidence of SARS-CoV-2 infection in the community. There is some evidence that given limited control measures, SARS-CoV-2 may spread robustly in secondary/high schools, and to a lesser degree in primary… Lire la suite »On the effect of age on the transmission of SARS-CoV-2 in households, schools and the community | The Journal of Infectious Diseases | Oxford Academic

Transmission of SARS-COV-2 Infections in Households — Tennessee and Wisconsin, Apr–Sept 2020 | MMWR

Summary What is already known about this topic? Transmission of SARS-CoV-2 occurs within households; however, transmission estimates vary widely and the data on transmission from children are limited. What is added by this report? Findings from a prospective household study with intensive daily observation for ≥7 consecutive days indicate that transmission of SARS-CoV-2 among household members was frequent from either children or adults. What are the implications for public health practice? Household transmission of SARS-CoV-2 is common and occurs early after illness onset. Persons should self-isolate immediately at the onset of COVID-like symptoms, at the time of testing as a… Lire la suite »Transmission of SARS-COV-2 Infections in Households — Tennessee and Wisconsin, Apr–Sept 2020 | MMWR

Un salon, un bar et une classe: ainsi se transmet le coronavirus dans l’air | Ciencia | EL PAÍS

    Les intérieurs sont plus dangereux, mais les risques peuvent être réduits en mettant en place toutes les mesures disponibles pour lutter contre la contagion des aérosols. Voici les probabilités d’infection dans ces trois scénarios quotidiens en fonction de la ventilation, des masques et de la durée de la rencontre Six personnes, dont une est contaminée, se réunissent dans une maison. 31% des foyers connus en Espagne apparaissent dans ce genre de réunions sociales, notamment dans les rencontres avec des membres de la famille et des amis. Indépendamment de la distance, si les cinq autres personnes passaient quatre heures… Lire la suite »Un salon, un bar et une classe: ainsi se transmet le coronavirus dans l’air | Ciencia | EL PAÍS

Covid-19 : l’Allemagne investit massivement dans un plan de ventilation et la France serait bien inspirée de l’imiter | Atlantico.fr

Atlantico.fr : Le gouvernement allemand a investi 500 millions d’euros dans l’amélioration des systèmes de ventilation des bâtiments publics, afin d’aider à arrêter la propagation du coronavirus. Sont concernés pour le moment : les bureaux publics, les musées, les théâtres, les universités et les écoles. Les gouttelettes expirées par les personnes infectées resteraient au moins 8 minutes dans l’air d’une pièce. L’objectif est de moderniser les systèmes de climatisation existants. Pourquoi est-ce important de faire cela ? (…) Source: Covid-19 : l’Allemagne investit massivement dans un plan de ventilation et la France serait bien inspirée de l’imiter | Atlantico.fr

Aerosol transmission of Covid-19: A room, a bar and a classroom: how the coronavirus is spread through the air | Society | EL PAÍS in English

The risk of contagion is highest in indoor spaces but can be reduced by applying all available measures to combat infection via aerosols. Here is an overview of the likelihood of infection in three everyday scenarios, based on the safety measures used and the length of exposure Scrolling 1 Six people get together in a private home, one of whom is infected. Some 31% of coronavirus outbreaks recorded in Spain are caused by this kind of gathering, mainly between family and friends. Irrespective of whether safe distances are maintained, if the six people spend four hours together talking loudly, without… Lire la suite »Aerosol transmission of Covid-19: A room, a bar and a classroom: how the coronavirus is spread through the air | Society | EL PAÍS in English

Robust neutralizing antibodies to SARS-CoV-2 infection persist for months | Science

Abstract SARS-CoV-2 has caused a global pandemic with millions infected and numerous fatalities. Questions regarding the robustness, functionality, and longevity of the antibody response to the virus remain unanswered. Here we report that the vast majority of infected individuals with mild-to-moderate COVID-19 experience robust IgG antibody responses against the viral spike protein, based on a dataset of 30,082 individuals screened at Mount Sinai Health System in New York City. We also show that titers are relatively stable for at least a period approximating 5 months and that anti-spike binding titers significantly correlate with neutralization of authentic SARS-CoV-2. Our data suggests… Lire la suite »Robust neutralizing antibodies to SARS-CoV-2 infection persist for months | Science

It Is Time to Address Airborne Transmission of Coronavirus Disease 2019 (COVID-19) | Clinical Infectious Diseases | Oxford Academic

We appeal to the medical community and to the relevant national and international bodies to recognize the potential for airborne spread of coronavirus disease 2019 (COVID-19). There is significant potential for inhalation exposure to viruses in microscopic respiratory droplets (microdroplets) at short to medium distances (up to several meters, or room scale), and we are advocating for the use of preventive measures to mitigate this route of airborne transmission. Studies by the signatories and other scientists have demonstrated beyond any reasonable doubt that viruses are released during exhalation, talking, and coughing in microdroplets small enough to remain aloft in air… Lire la suite »It Is Time to Address Airborne Transmission of Coronavirus Disease 2019 (COVID-19) | Clinical Infectious Diseases | Oxford Academic

SARS-CoV-2 vaccines in development | Nature

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late 2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. To mitigate the effects of the virus on public health, the economy and society, a vaccine is urgently needed. Here I review the development of vaccines against SARS-CoV-2. Development was initiated when the genetic sequence of the virus became available in early January 2020, and has moved at an unprecedented speed: a phase I trial started in March 2020 and there are currently more than 180 vaccines at various stages of development.… Lire la suite »SARS-CoV-2 vaccines in development | Nature