immunité

L’aventure scientifique des vaccins à ARN messager | Le Monde | Réalités Biomédicales

Lisa Ferdinando. DoD. © Wikimedia Commons C’est l’histoire d’un concept scientifique qui a débouché, en un temps record, sur le développement et la production à grande échelle de préparations vaccinales qui seront pour la première fois administrées chez l’homme dans un contexte très particulier, celui d’une maladie infectieuse pandémique. Des millions de doses des vaccins élaborés par Pfizer/BioNTech d’une part, Moderna d’autre part, sont en effet actuellement produites pour répondre à la demande de nombreux pays. Elles ont commencé à être administrées au Royaume-Uni, aux États-Unis, au Canada. Ces vaccins sont constitués d’ARN (ou acide ribonucléique). Plus précisément, ils renferment… Lire la suite »L’aventure scientifique des vaccins à ARN messager | Le Monde | Réalités Biomédicales

Robust neutralizing antibodies to SARS-CoV-2 infection persist for months | Science

Abstract SARS-CoV-2 has caused a global pandemic with millions infected and numerous fatalities. Questions regarding the robustness, functionality, and longevity of the antibody response to the virus remain unanswered. Here we report that the vast majority of infected individuals with mild-to-moderate COVID-19 experience robust IgG antibody responses against the viral spike protein, based on a dataset of 30,082 individuals screened at Mount Sinai Health System in New York City. We also show that titers are relatively stable for at least a period approximating 5 months and that anti-spike binding titers significantly correlate with neutralization of authentic SARS-CoV-2. Our data suggests… Lire la suite »Robust neutralizing antibodies to SARS-CoV-2 infection persist for months | Science

The Pandemic’s Biggest Mystery Is Our Own Immune System – The Atlantic

Even the word immunity creates confusion. When immunologists use it, they simply mean that the immune system has responded to a pathogen—for example, by producing antibodies or mustering defensive cells. When everyone else uses the term, they mean (and hope) that they are protected from infection—that they are immune. But, annoyingly, an immune response doesn’t necessarily provide immunity in this colloquial sense. It all depends on how effective, numerous, and durable those antibodies and cells are. From the September 2020 issue: How the pandemic defeated America Immunity, then, is usually a matter of degrees, not absolutes. And it lies at… Lire la suite »The Pandemic’s Biggest Mystery Is Our Own Immune System – The Atlantic